解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Flavonoids are metabolized in vivo to monocyclic phenolic acids. We investigated whether 18 phenolic acids of the benzoic, phenylacetic, phenylpropanoic or cinnamic series-known or potential metabolites of flavonoids-inhibit reactive oxygen species (ROS) released by human polymorphonuclear neutrophils (PMNs). Chemilum...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-1999-13956
更新日期:1999-02-01 00:00:00
abstract::The random amplified polymorphic DNA analysis (RAPD) is a method to study genetic variability within and between populations and species on the basis of the amplification of anonymous fragments from genomic DNA templates by means of polymerase chain reaction (PCR). We applied RAPD analysis in order to distinguish medi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960447
更新日期:1999-02-01 00:00:00
abstract::Hot water extract (ALR-0) of rhizomes of Atractylodes lanceo DC. was fractionated into MeOH-soluble fraction (ALR-1), supernatant fraction of EtOH precipitation (ALR-3 + 4), and crude polysaccharide fraction (ALR-5). Among these fractions, only ALR-5 showed potent stimulating activity for proliferation of bone marrow ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957564
更新日期:1998-12-01 00:00:00
abstract::An analytical method using HPLC with UV detection was developed to investigate the quassinoid content of Eurycoma longifolia Jack (Simaroubaceae) collected from various sources. Eurycomanone (1), longilactone (2), 14,15beta-dihydroxyklaineanone (3), 15beta-acetyl-14-hydroxyklaineanone (4), 6alpha-hydroxyeurycomalacton...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957570
更新日期:1998-12-01 00:00:00
abstract::A crude globulin fraction was isolated from the tubers of Pinellia ternata (Thunb.) Breit. Tubers of P. ternata are one of the well known Chinese traditional medicines. It is used on account of its anti-emetic effect. 6KDP was separated by means of gel filtration and chromatography on CM-Toyopearl 650 M from the crude...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957539
更新日期:1998-10-01 00:00:00
abstract::Sesquiterpene lactones 1-5 were isolated for the first time from the ethyl acetate of Vernonia fastigiata (Asteraceae). Compounds 3, 4 and 5 are new, compounds 1 and 2 have been found earlier in other Vernonia species but not in V. fastigiata. ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-957551
更新日期:1998-10-01 00:00:00
abstract::The ethanolic extract of Ilex aquifolium L. (Aquifoliaceae) concentration-dependently inhibited leukotriene B4 biosynthesis in isolated bovine PMNL with an IC50 value of about 60 micrograms/ml, whereas the effect on epidermal 12(S)-HETE biosynthesis was much less pronounced. The extract also inhibited the non-enzymati...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957509
更新日期:1998-08-01 00:00:00
abstract::Cordatolide A and B were re-isolated from Calophyllum cordato-oblongum, an endemic species of Sri Lanka, and found to inhibit HIV-1 reverse transcriptase with IC50 values of 12.3 and 19.0 microM, respectively. ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-957483
更新日期:1998-06-01 00:00:00
abstract::Extracts from Bupleurum fruticescens were examined for oral and topical anti-inflammatory activities. The BuOH extract proved to be active against carrageenan and tetradecanoylphorbol acetate acute edemas and allowed the isolation of three saponins identified by spectroscopic techniques as 3 beta-O-(O-alpha-L-rhamnopy...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957469
更新日期:1998-06-01 00:00:00
abstract::TLC autographic assays revealed in the CH(2)Cl(2) extract of Tinospora crispa Miers (Menispermaceae) the presence of three compounds exhibiting antioxidant and radical scavenging properties towards beta-carotene and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. They were isolated and identified as N-CIS-feruloyltyrami...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957466
更新日期:1998-06-01 00:00:00
abstract::The medicinal properties of curcumin obtained from Curcuma longa L. cannot be utilised because of poor bioavailability due to its rapid metabolism in the liver and intestinal wall. In this study, the effect of combining piperine, a known inhibitor of hepatic and intestinal glucuronidation, was evaluated on the bioavai...
journal_title:Planta medica
pub_type: 临床试验,杂志文章
doi:10.1055/s-2006-957450
更新日期:1998-05-01 00:00:00
abstract::Galphimine-B (G-B) is a bioactive compound isolated from the plant Galphimia glauca Cav. (Malpighiaceae) with central nervous system depressant properties previously described. In the present study, extracellular spiking activity records in either somatosensorial cortex or ventral tegmental area (VTA) neurons, were pe...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957440
更新日期:1998-05-01 00:00:00
abstract::Accumulation of furanic labdane diterpenes has been investigated in different parts of field-grown plants of MARRUBIUM VULGARE (Lamiaceae) and LEONURUS CARDIACA (Lamiaceae). Furanic labdane diterpenes were produced and accumulated only in the aerial parts. Greatest amounts were measured in leaves and flowers. Up to 4 ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957451
更新日期:1998-05-01 00:00:00
abstract::Synthetic butylidenephthalide (Bdph), 60 mg/kg per os (p.o.) given 3 h prior to injection of pituitrin (4 U/kg, i.v.), significantly prevented T-wave lowering on lead II electrocardiograph in unanesthetized rats. The effective dose, 60 mg/kg, was about 1/56th of the median lethal dose (LD50, p.o.) in rats. However, Bd...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957415
更新日期:1998-04-01 00:00:00
abstract::Various locations in Switzerland were screened for Petasites hybridus plants with high petasin and low pyrrolizidine alkaloid content. The mean petasin content of the various populations ranged from 7.4 to 15.3 mg/g dry weight in rhizomes and from 3.3 to 11.4 mg/g dry weight in leaves. Mean pyrrolizidine alkaloid cont...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957422
更新日期:1998-04-01 00:00:00
abstract::During the seasons 1989-1993, Valeriana officinalis plants were investigated for their contents of essential oil, valerenic acid and derivatives, and valepotriates. Harvesting of the subterranean parts was started in August of the year in which the seeds were sown, and continued until the last week of April of the sub...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957392
更新日期:1998-03-01 00:00:00
abstract::Seven coumarins were isolated from the aerial parts of Tordylium apulum; their structures were established by spectroscopic means. All compounds were tested in vitro for their cytotoxicity against two cell line systems. The antiproliferative effects for three of them were studied at the level of the cell cycle in asyn...
journal_title:Planta medica
pub_type: 信件
doi:
更新日期:1998-03-01 00:00:00
abstract::Many compounds of plant origin have been identified that inhibit different stages in the replication cycle of human immunodeficiency virus (HIV): 1) virus adsorption: chromone alkaloids (schumannificine), isoquinoline alkaloids (michellamines), sulphated polysaccharides and polyphenolics, flavonoids, coumarins (glycoc...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-2006-957384
更新日期:1998-03-01 00:00:00
abstract::Indole alkaloid contents were investigated in leaves of Tabernaemontana pachysiphon (Apocynaceae) trees in the natural habitat, Shimba Hills National Reserve, Kenya. The contents of the major alkaloids apparicine, tubotaiwine, tubotaiwine- N-oxide, and isovoacangine varied with site, leaf age, leaf growth form, positi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957393
更新日期:1998-03-01 00:00:00
abstract::The water extract of Biota orientalis showed a potent inhibitory effect on platelet activating factor (PAF) binding to rabbit platelets using [3H]PAF as a ligand in our previous screening studies for Korean medicinal antagonists by the activity-guided purification studies. Another active compound, compound 1 (IC50 = 2...
journal_title:Planta medica
pub_type: 信件
doi:
更新日期:1998-02-01 00:00:00
abstract::The crude methanol extract of the Kenyan shrub Leucas volkensii Gürke (Labiatae) displayed in a radiorespirometric bioassay antimycobacterial activity against Mycobacterium tuberculosis. Bioassay-guided fractionation of the crude extract led to the identification of (E)-phytol as the principal active component with a ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957354
更新日期:1998-02-01 00:00:00
abstract::Micellar electrokinetic capillary chromatography (MECC), using a phosphate buffer pH 7.0 and sodium dodecyl sulfate as the surfactant, was found suitable for the separation of structurally similar flavan-3-ols and related dimeric proanthocyanidins. A total of 20 substances has been tested, 17 of which were successfull...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957368
更新日期:1998-02-01 00:00:00
abstract::In the course of our screening program for acyl-CoA : cholesterol acyltransferase (ACAT) inhibitors from Korean herbal medicines, ACAT inhibitors were isolated from the hairy roots of Panax ginseng (Araliaceae) and identified as panaxynol, panaxydol, panaxydiol, and panaxytriol. These active compounds inhibit rat live...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957763
更新日期:1997-12-01 00:00:00
abstract::The chemical investigation of the essential oils from the aerial organs of Bellis perennis L., the common daisy, showed that polyacetylenes were one of the dominant class of compounds. The major constituents, methyl deca-4,6-diynoate and deca-4,6-diynoic acid, and their structural analogues, deca-4,6-diyne, dimethyl o...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957751
更新日期:1997-12-01 00:00:00
abstract::Two new acylated secoiridoid glycosides were isolated from the aqueous acetone extract of the whole herb of Gentiana algida. The structures of these new products were established by spectral and chemical methods as 6'-(2,3-dihydroxybenzoyl)sweroside and 6'-(2,3-dihydroxybenzoyl)swertiamarin, respectively. ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-957770
更新日期:1997-12-01 00:00:00
abstract::Extracellular polysaccharides (ECP) were isolated in yields of up to 4 mg/ml from the culture media of suspension-cultured cells from Digitalis lanata Ehrh. ECP content was increasing continuously over the first ten days of cultivation and then stayed constant until day 20. ECP were fractionated by ion-exchange chroma...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957730
更新日期:1997-10-01 00:00:00
abstract::A crude polysaccharide fraction (DAP-1) was prepared from roots of Dipsacus asperoides by hot water extraction and EtOH precipitation, and tested for anti-complementary activity, mitogenic activity of lymphocytes, and effects on acid phosphatase and phagocytic activities of macrophages. DAP-1 showed not only anti-comp...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957720
更新日期:1997-10-01 00:00:00
abstract::The chemical analyses of two Cynara species: C. humilis and C.cornigera revealed various combinations of flavones, flavonols, flavanones, coumarins, phenolic acids, and an aurone. All the identified constituents are reported for the first time from the two species, while the presence of the aurone is reported for the ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-957738
更新日期:1997-10-01 00:00:00
abstract::A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, 1H-NMR, and 13C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum....
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-957701
更新日期:1997-08-01 00:00:00
abstract::The novel diterpenoid taxol (paclitaxel) is now well-established as a potent chemotherapeutic agent. Total synthesis of the drug is not commercially feasible and, in the foreseeable future, the supply of taxol and its synthetically useful progenitors must rely on biological methods of production. The first three steps...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-2006-957684
更新日期:1997-08-01 00:00:00
abstract::(1)H- and (13)C-NMR spectral data are presented for six p-terphenylquinone derivatives (and for two monosubstituted quinones 1 and 2, used as model compounds) and for 9,10-phenanthraquinone and retenequinone. The chemical shifts were confirmed through correlation spectroscopy and NOE measurements. ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-957712
更新日期:1997-08-01 00:00:00
abstract::The studies were carried out to evaluate the constituents in the aerial part of Aconitum chiisanense (Ranunculaceae). From the butanol fraction of the methanol extract, kaempferol 3- O-beta-glucopyranoside-7- O-(6-trans-caffeoyl)-beta-glucopyranosyl-(1-->2)-alpha-rhamnopyranoside (I), quercetin 3- O-beta-glucopyranosi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957694
更新日期:1997-08-01 00:00:00
abstract::Four new neolignan glucosides, longiflorosides A, B, C and D, in addition to one known neolignan glucoside, dehydro-diconiferyl alcohol-4-O-beta-D-glucopyranoside were obtained from whole plants of Pedicularis longiflora. The structures of these compounds were determined mainly on spectral evidence. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957662
更新日期:1997-06-01 00:00:00
abstract::Oxygen radical injury and lipid peroxidation have been suggested as major causes of atherosclerosis, cancer, liver disease, and the aging process. More specifically, oxidative modification of low density lipoprotein (LDL) has been recognized as an important process of atherosclerosis. In this study, we determined the ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-957668
更新日期:1997-06-01 00:00:00
abstract::In this study we examined the ability of the furofuran lignan yangambin to influence the local and systemic responses induced by antigen or PAF in actively sensitized or normal rats. Given intraperitoneally 1 h before stimulation, yangambin inhibited the pleural neutrophil and eosinophil infiltration evoked by the i.p...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957654
更新日期:1997-06-01 00:00:00
abstract::During activity-guided fractionations to screen for antineoplastic agents, further studies by means of preparative HPLC led to the isolation of four known furostanol saponins: protoneodioscin, protodioscin, protoneogracillin, protogracillin, along with their corresponding artifacts: methyl protoneodioscin, methyl prot...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957636
更新日期:1997-04-01 00:00:00
abstract::Callus extracts of Crocus sativus exhibited the ability to transform all-trans-crocetin into its related glycosides between pH 7.0 and 7.6 in the presence of uridine-diphospho-glucose. The reactions involved the step-wise addition of a glucose moiety to a free carboxyl function and the 1-->6 addition of a glucose moie...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957633
更新日期:1997-04-01 00:00:00
abstract::The antiviral activities of two saponins, soyasaponin I and II, isolated from soybean (Glycine max Merrill) were studied in vitro against herpes simplex virus type 1 (HSV-1). Soyasaponin II was more potent than soyasaponin I as shown by reduction of HSV-1 production. Soyasaponin II was also found to inhibit the replic...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957622
更新日期:1997-04-01 00:00:00
abstract::A simultaneous separation of the enantiomers of kawain, dihydrokawain, methysticin, and dihydromethysticin as well as the achiral dienolides yangonin and demethoxyyangonin was carried out on a ChiraSpher NT column. This HPLC method can be used for the investigation of the enantiomeric purity of plant material and herb...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957606
更新日期:1997-02-01 00:00:00
abstract::The cytotoxicity of goniothalamin was found to be strong towards both cancerous (HGC-27, MCF-7, PANC-1, HeLa), and non-cancerous (3T3) cell lines, especially in cases of dividing cells. Drug exposure studies indicated that the cytotoxic action of goniothalamin was time- and dose-dependent. At the ultrastructural level...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957611
更新日期:1997-02-01 00:00:00